Itrakonazol, ketokonazol i u manjoj meri flukonazol i vorikonazol su snažni inhibitori izoenzima CYP3A4 citohroma P450 i mogu povećati koncentraciju benzodiazepina u plazmi.
Usled miorelaksantnog efekta postoji rizik od padova i posledičnih fraktura kuka kod starijih osoba.
You should not drink Alcoholic beverages when you are using co-codamol. This is due to the codeine it contains will boost the possibility of side-effects from your alcohol.
Some those with ailments that need to have extended-time period pain relief may need to choose dihydrocodeine for a long period.
Prijavljeno je da natrijum-valproat istiskuje diazepam sa mesta vezivanja za proteine plazme (povišena koncentracija u serumu: povećan rizik od pospanosti).
Usled naglog prekida terapije benzodiazepinima kod pacijenata sa epilepsijom i drugih pacijenata koji u anamnezi imaju epileptične napade može doći do pojave konvulzija ili epileptičnog statusa.
Preporučuje se primena alternativnih farmaceutskih oblika kod dece, kako bi se olakšalo davanje doza manjih od 5 mg.
Along with their practical effects, most medicines may cause unwanted side-effects Even though not Everybody ordeals them. The desk beneath consists of several of the most typical types connected to co-codamol.
Akutna porfirijaDiazepam se ne sme koristiti kao monoterapija u terapiji depresije i anksioznosti udružene sa depresijom, jer kod ove grupe pacijenata može uzrokovati pojavu suicida.
Some recreational medications, which include cannabis, also improve prevalent codeine side effects which include sleepiness and dizziness.
Are there other painkillers I can check out? Indeed, you'll find other painkillers it is possible to attempt. Some painkillers do the job better than Many others for specified pains. One example here is, the top painkiller to relieve your headache may not be the top one for your personal backache.
Open the pouch and take away the film. Fold the foil pouch alongside the stable line. Check out where the vertical slit is and thoroughly tear down the side from the pouch for the slit together the arrow to open up the pouch.
Tend not to give a next dose When you are worried about the child's respiratory, an crisis rescue treatment with respiratory support is needed, or there is extra sleepiness than standard.
Kod pacijenata kod kojih je duže trajala terapija benzodiazepinima može biti potreban i duži click here time period za povlačenje leka iz terapije. Ne preporučuje se dugotrajna hronična upotreba leka.